Our Services

Get 15% Discount on your First Order

[rank_math_breadcrumb]

case study AML

Case study on AML

Case Study 2: Advanced Pathophysiology of Acute Myelogenous Leukemia (AML)

A 45-year-old male presents to the hematology clinic with symptoms of progressive fatigue,
frequent bruising, and recurrent nosebleeds over the past few weeks. On physical examination,
he appears pale and has petechiae on his lower extremities. Blood tests reveal a white blood cell
count of 50,000/mm³ with 60% blasts, hemoglobin of 8.5 g/dL, and platelets of 25,000/mm³. A
bone marrow biopsy confirms the diagnosis of AML, showing hypercellularity with 70%
myeloblasts. Cytogenetic analysis reveals a FLT3-ITD mutation, placing him in the intermediate-
risk category.
In 1 -2 pages, answer the questions below in detail. You must use current evidence-based
resources to support your answers. Follow APA guidelines. Follow the grading rubric.
Questions:
1. What is the primary cellular abnormality in AML?
2. How does the accumulation of leukemic blasts affect normal hematopoiesis?
3. What role do genetic mutations play in the development of AML?
4. Why do patients with AML often present with symptoms like fatigue, infections, and
bleeding?
5. What is the significance of Auer rods in the diagnosis of AML?
6. What is the impact of AML on the immune system?
7. How do treatment strategies target the pathophysiological mechanisms of AML?

Grading Criteria

Develop a 1- to 2-page case study analysis, examining the patient signs and symptoms presented in the case study; discussing the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis.

The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response is supported by evidence and/or research, as appropriate, to support the explanation.

What role do genetic mutations play in the development of the disease?

Excellent

The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease.

What is the impact of the disease on the immune system? …… How do treatment strategies target the pathophysiological mechanisms of the disease?

Excellent

The response includes an accurate, complete, detailed, and specific explanation of the impact of the disease on the immune system. Response includes an accurate, complete, detailed, and specific explanation of how treatment strategies target the pathophysiological mechanisms of the disease.

Share This Post

Email
WhatsApp
Facebook
Twitter
LinkedIn
Pinterest
Reddit

Order a Similar Paper and get 15% Discount on your First Order

Related Questions

WK 5 PROJECT DOCUMENTS CONT

Develop SMART objectives you want your participants to accomplish from this DNP project  (DONE BY GERRY) Complete the ADDIE tool (DONE BY GERRY) WILL UPLOAD BOTH DOCUMENTS. START FROM HERE PLEASE 1) Make Power Point slides that you are going to present to them during this ~ 1-hour education session

research

i need to humanize my assignment, using the outline given below. Research Paper #2: Quantitative Literature Review Outline I. Introduction · Purpose of the review · Focus of the topic · Current state of knowledge (brief overview) · Organization of sources (highest → lowest level of evidence) · Use of

Nursing health care homework

THESE ARE MY THREE ARTICLE NOW I WILL GIVE YOU THE  OUTLINE AND TEMPLATE PLEASE FIULL IT OUT ACCORDINGLY.    Research  #2:  Quantitative Literature Review Outline I. Introduction • Purpose of the review • Focus of the topic • Current state of knowledge (brief overview) • Organization of sources (highest

Oxygen

🫁 Oxygenation Assignment #10 – Patient Education Handout Objective: Create a patient education handout on oxygen safety that teaches patients how to use and care for their oxygen safely at home or in a healthcare setting. 📝 Instructions Design a pamphlet, flyer, or handout that includes the key teaching points

Care plan

Care Planning Assignment #11 · Create a care plan for the patient: Mr. J. is a 68-year-old male being discharged home after a 7-day hospital stay for pneumonia. He will be using 2 L/min oxygen via nasal cannula at home. He reports feeling weak, becomes short of breath with activity,

NR 449 week 2

  This area provides you with an opportunity to reflect on what you have learned and what concepts you still need further exploration on.  Answer 1 question. Include a short summary of what has been learned, and include question(s) that are still unclear.   Post your answer to 1 of

goal

 PICOT question In adults’ patients undergoing general anesthesia, does forced-air warming before or during induction compared to passive blanket warming decrease incidence of hypothermia and improve intraoperative blood pressure stability during intraoperative period through PACU discharge? look at the attachement

Telehealth

What are the Pros and Cons to telehealth? How will you approach and perform a telehealth assessment? What are the limits to telehealth? What is the difference between the provider’s need for a successful telehealth visit versus the Patient’s perspective?

Nursing Assignment Instructions attached

Module 3:  Chart From the following chart, prepare 2 scatter plots, identifying the relationship between age and height, and age and weight. Using a bar graph for age frequency. AGE  HIGH WEIGHT 53 1.75 140 56 1.60 70 62 1.84 86 36 1.65 80 39 1.69 65 26 1.64 64

Nursing Assignment Instructions attached

Module 3:  Probability With the data presented here and in your readings in this module :  · Express in probability terms the probability of each variable (age, height, weight, & BMI)  · In the following graphs, with the additional data, mark the possible value of the mean in the graph

Nursing HOMEWORK3

Journal Entry Prepare · Refer to the “Population-Focused Nurse Practitioner Competencies” in the Learning Resources, and consider the quality measures or indicators advanced practice nurses must possess in your specialty. · Refer to your “Clinical Skills Self-Assessment Form” you submitted in Week 1 and consider your strengths and opportunities for

HCAD D7W7

 Healthcare organizations have traditionally encountered great difficulty in accurately capturing the costs of the services and goods that they provide. Traditional costing methods (i.e., direct, step-down, etc.) have proven marginally useful despite decades of use. In general, this has caused problems within healthcare organizations as it obscures the true cost

Middle Range Theory

I need help with making sure my concepts of theory is correct. I need to make sure it makes sense

Nursing

Barriers to and Drivers of Effective Collaboration in Interprofessional Healthcare Teams Instructions: At the AGMU virtual library, look for an article showing barriers to and drivers of effective collaboration in interprofessional healthcare teams; elaborate a summary of the article explaining the findings and propose possible solutions (or strategies) to avoid

POWER POINT 2

To Prepare: · Review the Resources and identify one change that you believe is called for in your organization/workplace. · This may be a change necessary to effectively address one or more of the issues you addressed in the Workplace Environment Assessment you submitted in Module 4. It may also

POWER POINT

To Prepare: · Reflect on the four peer-reviewed articles you critically appraised in Module 4, related to your clinical topic of interest and PICOT. · Reflect on your current healthcare organization and think about potential opportunities for evidence-based change, using your topic of interest and PICOT as the basis for

Lorem, ipsum

By engaging with your learning resources this the week you have explored: 1) what theory is, 2) the definition of nursing theory, 3) the classifications of nursing theory, and 4) a wide range of nursing theories and frameworks. Consider your current healthcare practice setting. Reflect on how you approach your

Nursing Nursing homework help

Provide 2 resources Original work only Application of Nursing Theory/Model · Explain how interdisciplinary theories influence nursing science particularly regarding education, practice and research. · How could a theoretical model from a related discipline impact advanced nursing practice regarding social determinants of health? · How would a science-based theory help