Description
General instructions:
- Each student must submit their own, original work.
- Copying or paraphrasing content from other students, online sources, or previous assignments is strictly prohibited and may result in a zero grade.
- Directly copying or submitting text generated entirely by AI without personal input or understanding is not allowed.
- Submission Format: Typed, PDF, submitted via BlackBoard
- In case you missed the deadline (the 15th week, Thursday, 12 noon), (11 Dec) your paper will not be accepted it.
- The structures can be drawn using online Chemical Sketch Tool (Not compulsory):
- Please email your assignment to the email address: [email protected]
- References: 1. Block, J. H., & Beale, J. M. (Eds.). (2011). Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry (12th ed.). Lippincott Williams & Wilkins. 2. Lemke, T. L., Williams, D. A., Roche, V. F., & Zito, S. W. (Eds.). (2013). Foye’s Principles of Medicinal Chemistry (7th ed.). Lippincott Williams & Wilkins.
Name:
ID:
General instructions:
• Each student must submit their own, original work.
• Copying or paraphrasing content from other students, online sources, or previous assignments is strictly
prohibited and may result in a zero grade.
• Directly copying or submitting text generated entirely by AI without personal input or understanding is not
allowed.
• Submission Format: Typed, PDF, submitted via BlackBoard
• In case you missed the deadline (the 15th week, Thursday, 12 noon), (11 Dec) your paper will not be
accepted it.
• The structures can be drawn using online Chemical Sketch Tool (Not compulsory):
• Please email your assignment to the email address: [email protected]
• References: 1. Block, J. H., & Beale, J. M. (Eds.). (2011). Wilson and Gisvold’s Textbook of Organic
Medicinal and Pharmaceutical Chemistry (12th ed.). Lippincott Williams & Wilkins. 2. Lemke, T. L.,
Williams, D. A., Roche, V. F., & Zito, S. W. (Eds.). (2013). Foye’s Principles of Medicinal Chemistry (7th
ed.). Lippincott Williams & Wilkins.
Q1. Drug Profile Assignment (Total = 10 Marks)(CLO 3.1)
Instructions:
Write about one drug of your choice from any therapeutic class in your course.
Your answer must include the following components. Each part carries the mark indicated.
Provide clear, concise, and scientifically accurate information. Include a diagram of the chemical
structure and references.
No.
Component
1
Name and Structure
2
Category
3
Mechanism of Action
(MOA)
4
Structure–Activity
Relationship (SAR)
5
Uses
6
Side Effects
7
Metabolism
8
Pharmacokinetics
Description
Marks
State the generic name of the drug and draw or
1
insert its chemical structure.
Mention the pharmacological or therapeutic class
1
of the drug (e.g., β-blocker, antibiotic, NSAID).
Explain how the drug works at the molecular or
receptor level (drug-target interactions if
2
applicable).
Discuss how changes in the chemical structure
2
affect the drug’s activity, potency, or selectivity.
List the main clinical indications or diseases treated
1
by the drug.
Mention the common or significant adverse effects
1
associated with the drug.
Describe the metabolic pathway, key enzymes
1
involved, and metabolites (if applicable).
Summarize absorption, distribution, metabolism,
1
and excretion (ADME) properties.
No.
Total
Component
Description
Marks
10 Marks
Q2. Write the possible metabolic pathways and metabolites for the given
compounds. (Total = 5 Marks)(CLO 2.1)
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