Watch the following video to learn more about how to read a codon chart 300 words
Paul is a first-year graduate student working in a bacterial pathogenesis lab focused on finding therapeutic drugs to target a specific bacterial organism. Since Paul was new to research he did not fully understand why it was important to use a newly grown bacterial culture for each experiment and thus decided to use a 5-day old bacterial culture to repeat his experiments. When his experimental results were drastically different he decided to sequence the DNA of the 5-day old bacteria and compare it to his original culture. His results showed that a metabolic gene with the following RNA sequence
AUGUCUGGUGGUGAA
CGCGUG
underwent a spontaneous mutation and the underlined ‘
C
’ was changed to an ‘
A’.
Answer the following questions:
1. What is the amino acid sequence
before
the mutation?
2. What is the amino acid sequence
after
the mutation?
3. What
specific
type of mutation occurred?
4. What
enzyme
was responsible for this mutation? Explain why you chose that enzyme.