SC235: Unit Nine Assignment: Inheritance and PG Library Search
For this assignment, you will select a specific inherited disease/disorder from the list below. Then, using the research tools at the Library you will provide a brief overview of the disease, identify the mode of inheritance for your selected disease and will identify any genes associated with the development of the selected disease. Then, you will research whether there is a gene therapy available or being evaluated for your selected disorder. Lastly, you will examine the validity of sources. Visit the Purdue Global Library by clicking on “My Studies” and then selecting the “Library” link on the Campus homepage. You may also access the Library Resources for SC235 by clicking on the following link: Note that you have to be logged into your PG account to access the PG Library.
Select ONE inherited disease from the following list:
● Adenosine Deaminase (Ada) Deficiency
● Alpha-1 Antitrypsin Deficiency
● Antiphospholipid Syndrome
● Charcot-Marie-Tooth Disease
● Congenital Deafness – (Nonsyndromic)
● Cystic Fibrosis
● Duchenne Muscular Dystrophy
● Fabry Disease
● Familial Hypercholesterolemia
● Fragile X Syndrome
● Galactosemia
● Hemochromatosis
● Hemophilia A
● Hereditary Breast Cancer
● Huntington’s Disease
● Hypophosphatemic Rickets
● Maple Syrup Urine Disease (Msud)
● Marfan Syndrome
● Neurofibromatosis Type 1 (Nf1)
● Pachyonychia Congenita
● Phenylketonuria
● Phenylketonuria (Pku)
● Severe Combined Immunodeficiency
● Sickle-Cell Anemia
● Smith-Lemli-Opitz Syndrome (SLOS)
● Tay-Sachs Disease
● X-linked Thrombocytopenia
Part I: Introduction: Disease Overview and Mode of Inheritance
- Research your selected disease. Then, provide an introduction to the disease, including the major signs and symptoms and why the disease is considered an inherited disease.
Selected Disease:
Introduction to the disease:
Why the disease is considered to be an inherited disorder:
- What is the mode of inheritance for the disease you selected? Provide a brief (approx. 50 words) description of the mode of inheritance. What specific genes have been identified in the development of the disease? Why does a mutation in these genes lead to the signs and symptoms of the disorder?
Identify the mode of inheritance:
Explanation of mode of inheritance:
List genes associated with the development of the disease:
Why does a mutation in these genes lead to the signs and symptoms of your selected disease?
Part II: Purdue University Global Library Search: Search the Purdue Global Library for your selected inherited disease by using the “Search the Library” bar. List the search term(s)/disease you used. How many results did you get?
Answer here:
Now, use a combination of search terms to find the mode of inheritance for your selected disease. List the search terms you used.
Answer here:
Which method (initial term or combination) resulted in the most accurate results for your research on your selected disease? Identify at least two sources from the PG Library search that you will use for this assignment.?
Answer here:
Part III: Evaluating Sources
- Perform a search on a traditional search engine (e.g., Google, Bing). What differences do you observe between thePurdue Global Library search and the one using a search engine ?
Answer here:
- Which of these searches is more appropriate for academic research? Why? Provide a thorough explanation of what makes the search more appropriate. Support your response with evidence.
Answer here:
- Perform another search and research if there are any new therapies, including gene therapy, available or being evaluated to treat your selected disorder. Summarize at least one of these therapies. Discuss specific ethical implications related to the use of this therapy/treatment.
Answer here:
References
List your references in APA format. You must include at least two credible sources from your PG Library search.
